Release date: 2007-11-08
Tomography can be used to determine cancer prognosis A study conducted by the Department of Radiation Oncology, Department of Radiation Oncology, University of Washington, DC, showed that positron emission tomography (PET) is helpful in predicting the outcome and prognosis of patients with cervical cancer, similar results in head and neck cancer, esophagus It has been reported in patients with cancer and lung cancer.
F-18 Fluorodeoxyglucose (FDG) is the most commonly used PET tracer and high uptake shows strong or bright signals. Elizabeth et al retrospectively analyzed 287 patients with cervical cancer, and recorded the FDG standard uptake value (SUV) while diagnosing the primary tumor. The patient was given surgery, chemotherapy or radiotherapy according to the standard treatment protocol, and the tumor staging was performed according to the standard guidelines. Tumor size and surrounding tissue infiltration, ranging from early IA2 to advanced IVB.
The results showed that SUV had more prognostic value than age, tumor volume, histological features, staging and other factors; patients were divided into three groups: low, medium and high risk groups. The 5-year survival rate of the lowest SUV group was 95%. 70%, the highest group of SUV is 44%; the higher the primary tumor SUV, the higher the recurrence rate, the lower the survival rate.
The researchers say that high SUVs indicate that tumors take up glucose faster, which may mean biologically different tumors that are more aggressive. Further research to find out the reasons for this difference will eventually lead to the emergence of new treatments. ——China Medicine 123 Network
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